Herbicides | Enlist® weed control system

Enlist® Herbicides

Tractor spraying early soybeans

Fight weeds, not your herbicides.

Get weed control with inherently low volatility and reduced physical drift potential.

The Enlist® weed control system gives farmers choices for weed control using 2,4-D choline with Colex-D® technology. Enlist Duo® and Enlist One® herbicides are designed to land and stay on target for unrivaled control of the toughest weeds — including Palmer amaranth, waterhemp and giant ragweed — in your fields.

Available as a convenient, proprietary blend, Enlist Duo combines 2,4-D choline and glyphosate. Enlist One is a straight-goods 2,4-D choline providing additional tank-mix flexibility.

With a wide application window and no calendar cutoff dates, tough and glyphosate-resistant weeds aren’t so tough anymore.

Review the application guide. Make sure your application of an Enlist herbicide is successful by reading our step-by-step guide before you apply. Always follow label requirements during application.

Enlist® Herbicides

Take control of weeds by learning which Enlist herbicide is best for your fields.


No calendar cutoff dates.

Enlist herbicides can be applied on crops with the Enlist trait from burndown through postemergence. The labeled application window for Enlist herbicides is based on crop growth stage, with no calendar cutoff dates. To help maximize the yield potential on your farm, make Enlist herbicides the cornerstone of your weed control plan that includes multiple sites of action.

Follow our step-by-step application guide to apply these herbicides successfully.

Wide Application Window

Spray on your schedule — through R2 on Enlist E3® soybeans, early bloom on Enlist® cotton and V8 or 30 inches tall on Enlist® corn. Learn more about the application window and recommended program approach for crops with the Enlist trait. 

Sprayer at sunset

Product Use Guide

For unrivaled weed control, one herbicide system doesn’t just stand out — it stands alone. Take control of tough weeds by learning more about a system that is ready to work, right now, for you.

Download Use Guide
Enlist application icons

Apply with Confidence

Start clean and stay clean by following the application guide to ensure a successful application. Enlist® herbicides can be used in burndown, preemergence and postemergence on crops with the Enlist trait.

View Application Guide

Near-zero volatility. Unmovable principles. 

The Enlist® trait allows you to confidently use Enlist herbicides with better on-target results than traditional 2,4-D products. With the inherent near-zero volatility of 2,4-D choline, Enlist One® and Enlist Duo® herbicides provide effective weed control that stay where they are sprayed. Volatility is reduced by 96% vs. 2,4-D ester.

In an acid-to-acid comparison, dicamba is 236X more volatile than 2,4-D. A tank mix of Engenia® herbicide and glyphosate is 98% more volatile than Enlist Duo herbicide. The lower volatility profile of Enlist herbicides means they have the built-in ability to stay where they're sprayed. Unlike in-crop dicamba herbicides, Enlist herbicides do not require the addition of a volatility reduction agent (VRA) in the tank and there are no temperature restrictions for application. For a complete comparison of the Enlist® system vs. in-crop dicamba system — from buffers to application — view this fact sheet

In addition, applicators can tank-mix 2,4-D choline with qualified glyphosate DMA (amine), glufosinate ammonium and ammonium sulfate (AMS) products. These products will not break the inherent low volatility of 2,4-D choline. With more than 1,700 qualified tank-mix products with Enlist One herbicide, you can find the right options to fit your weed pressure. Find a full list of qualified tank-mix products at EnlistTankMix.com.

Physical Drift

With Enlist herbicides, you also can control physical drift better. Enlist herbicides are formulated with Colex-D® technology to reduce driftable fines — those prone to move away from the target during application — without decreases in droplet size. Research trials prove Colex-D® technology helps Enlist herbicides land and stay on target.

  • TANK MIX OF GLYPHOSATE + TRADITIONAL 2,4-D
  • ENLIST DUO® HERBICIDE WITH COLEX -D® TECHNOLOGY

Tank mix of glyphosate + traditional 2,4-D (left); Enlist Duo® herbicide with Colex-D® echnology (right)

In addition, the use of qualified nozzles for Enlist One and Enlist Duo herbicides help reduce the drift potential even more. Using Enlist Duo® herbicide featuring Colex-D® technology along with qualified nozzles reduces the potential for physical drift by 90% compared with a tank mix of traditional 2,4-D and glyphosate.

Follow all label requirements that help minimize the potential for physical drift.

Want more options and honest answers? Read how farmers are winning the fight against weeds.

Follow label quote card

On-target application

- Jack Kent, Arkansas

Learn more
Controlled weed in Cotton field

Weed-free Enlist E3® soybeans

- Adam Schwering, Indiana

Learn more
Painted line quote card for Enlist

Excellent weed control

- Tom Connors, Illinois

Read article

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Enlist Duo® and Enlist One® herbicides are not registered for sale or use in all states or counties. Contact your state pesticide regulatory agency to determine if a product is registered for sale or use in your area. Enlist Duo and Enlist One herbicides are the only 2,4-D products authorized for use with Enlist crops. Consult Enlist herbicide labels for weed species controlled. Always read and follow label directions. 

Engenia is a Restricted Use Pesticide.