The 2,4-D choline tolerance in Enlist® crops provides a wide application window for Enlist herbicides. Unlike dicamba that has a June 30 national cutoff date (some states have even tighter restrictions), there are no calendar cutoff dates for applications of Enlist herbicides. Remember to always read and follow label requirements. Here are the application windows for Enlist herbicides:

• Enlist E3^® soybeans: Through R1 growth stage.
• Enlist^® cotton: Up to first white bloom.
• Enlist corn: No larger than V8 growth stage or 30 inches tall, whichever happens first.

The 2,4-D choline with Colex-D® technology in Enlist herbicides provides near-zero volatility, reduced physical drift potential, and better handling characteristics.  Enlist One® herbicide can be tank-mixed with qualified glyphosate and glufosinate herbicides without affecting the near-zero volatility properties of 2,4-D choline. In comparison, in-crop dicamba products cannot be tank-mixed with glufosinate, and only K-salt glyphosates are qualified tank-mix partners.

For sensitive areas, the dicamba system requires a 240-foot downwind buffer. Additional buffers are required in endangered species areas, as designated by EPA's Bulletins Live website: a 57-foot omnidirectional buffer, as well as a 310-foot downwind buffer are required. The Enlist® system requires a 30-foot downwind buffer (in the direction in which the wind is blowing) from any area except:

• Roads (paved or gravel surfaces)
• Planted agricultural fields (except those crops mentioned in the "Susceptible Plants” section)
• Agricultural fields that have been prepared for planting
• Areas covered by the footprint of a building, shade house, greenhouse, silo, feed crib or other man-made structure with walls and/or roof

The Enlist^® system allows for tank-mixing with both qualified glufosinate and AMS products, but the dicamba system does not. Glyphosate pre-mix products – Enlist Duo^® herbicide – are available with the Enlist system, but are not with the in-crop dicamba system. In terms of required additives, dicamba requires a pH buffering agent with every application. With Enlist having inherent near-zero volatility, no buffering agents or volatility reducing agents are needed.  

In-crop dicamba herbicides are registered as federally restricted-use pesticides, which means they can only be applied by those with a Certified Applicator license or those under the direct supervision of a certified applicator. Enlist® herbicides are not federally restricted-use pesticides. There are also no time-of-day application limits with Enlist herbicides; however, dicamba must be applied only from 1 hour after sunrise to 2 hours before sunset.